Macleod studied at the University of Glasgow and the Free Church College before being ordained as a minister of the Free Church of Scotland in 1964. He served as professor of systematic theology at the Free Church College from 1978 to 2011, and as principal from 1999 to 2010.
In 1996, Macleod was cleared of allegations that he had sexually assaulted four women. The Sheriff court found that "the women had all lied in the witness box to further the ends of Professor Macleod's enemies in the Free Church of Scotland." A number of people who believed Macleod should be put on trial by the General Assembly then formed the Free Church Defence Association and ultimately a new denomination, the Free Church of Sc
